Sunday, June 29, 2008

The Free-Fall in Fertility

According to studies and continued observation by local endocrinologists, the men of mid-Missouri are undergoing a crash in sperm levels. The problem started cropping up in the mid-1990s, and was cemented during a 1999 study which compared healthy sperm levels between major metropolitan areas. For use in comparison, Columbia, MO was used to help establish a baseline, assuming that the presence of fewer toxic pollutants would lead to higher, healthier levels.

However, it was not to be. Columbia residents' levels maxed out at 57% of the levels of males in New York City, for example; observe the graph at the right for more detail. Most stunning is that Missouri men came from different backgrounds and lifestyles, were of varied ages and professions, and were both long-term and short-term residents of Columbia.

Researchers participating in the 1999 study reexamined Missouri sperm and subjected it to detailed tests for pesticides and chemicals known to be in use in the region. Three pesticides were found to have statistically significant links with the low sperm counts, with two more possible contributors identified as well. One of these pesticides, diazinon, was banned from residential use in 2004, yet still allowed to be used in agriculture. Whatever the case, a follow-up study was conducted by the Centers for Disease Control, with results expected this summer. We will be following this closely, rest assured, for professional and personal reasons.

As the researchers in the article state, blaming one chemical or one pesticide is likely in error. Much more likely are the complex and subtle interactions between varying doses of several chemicals incipient to the lifestyle in the region, coupled with other environmental and lifestyle factors. It is impossible to predict how cocktails of chemicals administered over a lifetime in low doses will interact within the human body. If you would like to know more on this kind of research, check out the research on chemicals in adults, newborns, and pets.

But let us be clear- this is more than likely not a mid-Missouri problem. Whatever the cause is, it is highly possible that these results could be repeated throughout the mid-America region. If there are demonstrable links between pesticide use and low fertility in males, this is something that demands our immediate attention. We will be awaiting the CDC report, and hope to talk about this more in the future.

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